{"id":3098,"date":"2018-11-30t10:20:08","date_gmt":"2018-11-30t10:20:08","guid":{"rendered":"\/\/www.aselpijama.com\/?page_id=3098"},"modified":"2024-08-09t16:11:19","modified_gmt":"2024-08-09t15:11:19","slug":"selexipag","status":"publish","type":"page","link":"\/\/www.aselpijama.com\/about-ph-2\/treatment-for-pulmonary-hypertension\/oral-therapies\/selexipag\/","title":{"rendered":"selexipag"},"content":{"rendered":"
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selexipag is part of a class of treatments called prostanoids receptor agonists. it makes its beneficial effects by working in a similar way to other prostanoids. however, it has been designed to reduce the amount and severity of systemic (whole body) side effects caused by medicines such as iloprost or epoprostenol.<\/p>

how to take it<\/h3>

selexipag is a tablet which is taken twice a day, ideally with food. the tablets must be swallowed whole, not chewed or crushed. the appropriate dose varies between patients, in the same way as intravenous prostanoids. for this reason, everyone starts on a very low dose, which is increased slowly over a few weeks until the maximum tolerated dose is reached. whilst this \u201cuptitration\u201d can be done at home, there is regular contact between patients and their ph centre to ensure this process is carried out safely. patients are encouraged to increase the dose to the point where some side effects are experienced, then be reviewed. selexipag tablets come in a variety of strengths so patients can easily up-titrate their dose, until the appropriate strength can be prescribed as one tablet twice a day.<\/p>

do not take selexipag if you:
\u2022<\/strong> have liver problems
\u2022 have severe coronary heart disease or unstable angina.
\u2022 have had a myocardial infarction within the last six months.
\u2022 have had a cerebrovascular events (e.g. transient ischaemic attack, stroke) within the last three months.
\u2022 have severe arrhythmias.
\u2022 have decompensated cardiac failure that is not under close medical supervision.
\u2022 have congenital or acquired valvular defects with clinically relevant myocardial function disorders not related to pulmonary hypertension.
\u2022 are pregnant or plan to become pregnant. it is not known if selexipag will harm your unborn baby.
\u2022 are breastfeeding or plan to breastfeed. it is not known if selexipag passes into your breast milk. you and your doctor should decide if you would take selexipag or breastfeed. you should not do both.<\/p>

side effects<\/h3>

the most common side effects are:
\u2022 headache.
\u2022 nausea and vomiting.
\u2022 pain in arms or legs.
\u2022 low red blood cell count.
\u2022 diarrhoea.
\u2022 muscle and joint pain.
\u2022 jaw pain.
\u2022 temporary reddening of the skin (flushing).
\u2022 reduced appetite.
\u2022 rash on.<\/p>

other useful information<\/h3>

selexipag is only available on prescription and should only be initiated by a specialist ph centre. if a dose is missed, patients should take a missed dose as soon as possible unless the next dose is within the next six hours. however, if treatment is missed for more than three days, restart selexipag at a lower dose and contact your ph centre for advice.<\/p>

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 <\/p>","protected":false},"excerpt":{"rendered":"

selexipag is part of a class of treatments called prostanoids receptor agonists. it makes its beneficial effects by working in a similar way to other prostanoids. however, it has been designed to reduce the amount and severity of systemic (whole body) side effects caused by medicines such as iloprost or epoprostenol. how to take it […]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":9860,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-3098","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"\/\/www.aselpijama.com\/wp-json\/wp\/v2\/pages\/3098"}],"collection":[{"href":"\/\/www.aselpijama.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"\/\/www.aselpijama.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"\/\/www.aselpijama.com\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"\/\/www.aselpijama.com\/wp-json\/wp\/v2\/comments?post=3098"}],"version-history":[{"count":7,"href":"\/\/www.aselpijama.com\/wp-json\/wp\/v2\/pages\/3098\/revisions"}],"predecessor-version":[{"id":90115,"href":"\/\/www.aselpijama.com\/wp-json\/wp\/v2\/pages\/3098\/revisions\/90115"}],"up":[{"embeddable":true,"href":"\/\/www.aselpijama.com\/wp-json\/wp\/v2\/pages\/9860"}],"wp:attachment":[{"href":"\/\/www.aselpijama.com\/wp-json\/wp\/v2\/media?parent=3098"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}